Intrauterine Insemination (IUI)

This is the least invasive and technically easiest (and therefore cheapest) form of treatment, with minimal complications.

In an Intrauterine Insemination cycle, a sample of motile sperm is prepared by the embryologist and placed directly inside the uterus using a very fine catheter. The sperm is deposited before the release of an egg or eggs in a natural or stimulated cycle. Conception occurs naturally inside the body.

IUI is usually the first step in treating couples with unexplained infertility.

IUI can be offered on a natural or stimulated cycle.

On a stimulated cycle (super ovulation), the size and number of follicle are measured using ultrasonography; a Human Chorionic Gonadotrophin (HCG) injection is given to mature the eggs when the follicles reach a certain size. IUI is performed 24-36 hours after the administration of the HCG injection.

The success rate of IUI is 10% – 12% per cycle. It is recommended that 3 – 6 cycles of treatment are attempted before considering other options.

Indications for intrauterine insemination

  • Unexplained infertility
  • Male infertility (mild)
  • Failure to conceive after ovulation induction treatment
  • Immunological (anti sperm antibodies)
  • Ejaculatory failure
  • Retrograde ejaculation
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